{"id":7354,"date":"2022-05-20T16:30:00","date_gmt":"2022-05-20T14:30:00","guid":{"rendered":"https:\/\/www.nexmif.it\/uncategorized\/speranza-per-disfunzioni-neurosviluppo\/"},"modified":"2022-05-30T09:54:25","modified_gmt":"2022-05-30T07:54:25","slug":"hope-for-neurodevelopmental-dysfunctions","status":"publish","type":"post","link":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/","title":{"rendered":"A hope for neurodevelopmental dysfunctions"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"7354\" class=\"elementor elementor-7354 elementor-6173\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1f8b4fab elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1f8b4fab\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-13774e42 column-style-top column-top\" data-id=\"13774e42\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3ece9b03 elementor-widget elementor-widget-text-editor\" data-id=\"3ece9b03\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 11-03-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<strong>IAMA Therapeutics<\/strong>, a start-up company that will develop a new drug candidate for neurodevelopmental dysfunctions such as autism spectrum disorders, is underway. It stems from the work of two research groups of the <a href=\"https:\/\/www.facebook.com\/IITalk\/?fref=mentions&#038;__xts__[0]=68.ARAzmcl8ekX6udCnn66_MgKtEU6VpA-aMzWRVuXV0xNDiT0QYj0BUs3KjA4c9MbEnKuygLMJrG2BmW1Jhh3WJub-IVVdvtQH9uYHrgHgjojPadeCAXgHo_URpMWyVhxADRGHQP8bvoWTw_EsbH6zYU5UYrZo_JFSBt9cgliZVf6RSODxKFzN-SFmJ7UpQo66Ue8s7WqIrqDxwQDp6WDRaLjHUBLmwbsy6i_EHV8-oC-glZ1ZJ2w2V7SxwZtKel5cHi9VC-KyBTm3ruxMhIHZc21uGBTudIncMDKt5kaC5zflliS9sFs\">ITALIAN INSTITUTE OF TECHNOLOGY<\/a> (IIT) of Genoa: &#8220;Brain Development and Disease&#8221; and &#8220;Molecular Modeling and Drug Discovery&#8221;, led respectively by scientists <a href=\"https:\/\/www.telethon.it\/cosa-facciamo\/ricerca\/ricercatori\/laura-cancedda\/\"><strong>Laura Cancedda<\/a> and Marco De Vivo<\/strong>. The project, supported by the Telethon Foundation, was financed by Claris Ventures Sgr and CDP Venture Capital Sgr through its Evolution Fund. Clinical trials of the potential drug called <strong>IAMA-6<\/strong> will begin in the next 24 months.\nRead the Telethon article &#8220;<a href=\"https:\/\/www.telethon.it\/storie-e-news\/news\/dalla-fondazione\/al-via-iama-therapeutics-che-sviluppera-un-nuovo-candidato-farmaco-per-le-disfunzioni-del-neurosviluppo\/\">IAMA Therapeutics is underway, to develop a new drug candidate for neurodevelopmental dysfunctions<\/a>&#8220;.\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>IAMA Therapeutics, a start-up company that will develop a new drug candidate for neurodevelopmental dysfunctions such as autism spectrum disorders, is underway. It stems from the work of two research groups of the ITALIAN INSTITUTE OF TECHNOLOGY (IIT) of Genoa: &#8220;Brain Development and Disease&#8221; and &#8220;Molecular Modeling and Drug Discovery&#8221;, led respectively by scientists Laura [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":8114,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[91],"tags":[],"class_list":["post-7354","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-scientific-journals"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>A hope for neurodevelopmental dysfunctions - Unione Italiana Nexmif<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A hope for neurodevelopmental dysfunctions - Unione Italiana Nexmif\" \/>\n<meta property=\"og:description\" content=\"IAMA Therapeutics, a start-up company that will develop a new drug candidate for neurodevelopmental dysfunctions such as autism spectrum disorders, is underway. It stems from the work of two research groups of the ITALIAN INSTITUTE OF TECHNOLOGY (IIT) of Genoa: &#8220;Brain Development and Disease&#8221; and &#8220;Molecular Modeling and Drug Discovery&#8221;, led respectively by scientists Laura [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/\" \/>\n<meta property=\"og:site_name\" content=\"Unione Italiana Nexmif\" \/>\n<meta property=\"article:published_time\" content=\"2022-05-20T14:30:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-05-30T07:54:25+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.nexmif.it\/wp-content\/uploads\/2022\/05\/speranza_disfunzioni_neurosviluppo-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1440\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"tecnico\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"tecnico\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/\"},\"author\":{\"name\":\"tecnico\",\"@id\":\"https:\/\/www.nexmif.it\/en\/#\/schema\/person\/d7d9d7ada6f302c812dbc5408405c955\"},\"headline\":\"A hope for neurodevelopmental dysfunctions\",\"datePublished\":\"2022-05-20T14:30:00+00:00\",\"dateModified\":\"2022-05-30T07:54:25+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/\"},\"wordCount\":118,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/www.nexmif.it\/en\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.nexmif.it\/wp-content\/uploads\/2022\/05\/speranza_disfunzioni_neurosviluppo-scaled.jpg\",\"articleSection\":[\"Scientific journals\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/\",\"url\":\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/\",\"name\":\"A hope for neurodevelopmental dysfunctions - Unione Italiana Nexmif\",\"isPartOf\":{\"@id\":\"https:\/\/www.nexmif.it\/en\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.nexmif.it\/wp-content\/uploads\/2022\/05\/speranza_disfunzioni_neurosviluppo-scaled.jpg\",\"datePublished\":\"2022-05-20T14:30:00+00:00\",\"dateModified\":\"2022-05-30T07:54:25+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#primaryimage\",\"url\":\"https:\/\/www.nexmif.it\/wp-content\/uploads\/2022\/05\/speranza_disfunzioni_neurosviluppo-scaled.jpg\",\"contentUrl\":\"https:\/\/www.nexmif.it\/wp-content\/uploads\/2022\/05\/speranza_disfunzioni_neurosviluppo-scaled.jpg\",\"width\":2560,\"height\":1440,\"caption\":\"Multi ethnic group of scientists working in laboratory interior\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.nexmif.it\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"A hope for neurodevelopmental dysfunctions\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.nexmif.it\/en\/#website\",\"url\":\"https:\/\/www.nexmif.it\/en\/\",\"name\":\"Unione Italiana Nexmif\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.nexmif.it\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.nexmif.it\/en\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.nexmif.it\/en\/#organization\",\"name\":\"Unione Italiana Nexmif\",\"url\":\"https:\/\/www.nexmif.it\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.nexmif.it\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.nexmif.it\/wp-content\/uploads\/2015\/12\/logo-big_w.png\",\"contentUrl\":\"https:\/\/www.nexmif.it\/wp-content\/uploads\/2015\/12\/logo-big_w.png\",\"width\":489,\"height\":202,\"caption\":\"Unione Italiana Nexmif\"},\"image\":{\"@id\":\"https:\/\/www.nexmif.it\/en\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.nexmif.it\/en\/#\/schema\/person\/d7d9d7ada6f302c812dbc5408405c955\",\"name\":\"tecnico\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.nexmif.it\/en\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/639d331f41d0f8de0b5c45c1b2f1d260?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/639d331f41d0f8de0b5c45c1b2f1d260?s=96&d=mm&r=g\",\"caption\":\"tecnico\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"A hope for neurodevelopmental dysfunctions - Unione Italiana Nexmif","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/","og_locale":"en_US","og_type":"article","og_title":"A hope for neurodevelopmental dysfunctions - Unione Italiana Nexmif","og_description":"IAMA Therapeutics, a start-up company that will develop a new drug candidate for neurodevelopmental dysfunctions such as autism spectrum disorders, is underway. It stems from the work of two research groups of the ITALIAN INSTITUTE OF TECHNOLOGY (IIT) of Genoa: &#8220;Brain Development and Disease&#8221; and &#8220;Molecular Modeling and Drug Discovery&#8221;, led respectively by scientists Laura [&hellip;]","og_url":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/","og_site_name":"Unione Italiana Nexmif","article_published_time":"2022-05-20T14:30:00+00:00","article_modified_time":"2022-05-30T07:54:25+00:00","og_image":[{"width":2560,"height":1440,"url":"https:\/\/www.nexmif.it\/wp-content\/uploads\/2022\/05\/speranza_disfunzioni_neurosviluppo-scaled.jpg","type":"image\/jpeg"}],"author":"tecnico","twitter_card":"summary_large_image","twitter_misc":{"Written by":"tecnico","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#article","isPartOf":{"@id":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/"},"author":{"name":"tecnico","@id":"https:\/\/www.nexmif.it\/en\/#\/schema\/person\/d7d9d7ada6f302c812dbc5408405c955"},"headline":"A hope for neurodevelopmental dysfunctions","datePublished":"2022-05-20T14:30:00+00:00","dateModified":"2022-05-30T07:54:25+00:00","mainEntityOfPage":{"@id":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/"},"wordCount":118,"commentCount":0,"publisher":{"@id":"https:\/\/www.nexmif.it\/en\/#organization"},"image":{"@id":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#primaryimage"},"thumbnailUrl":"https:\/\/www.nexmif.it\/wp-content\/uploads\/2022\/05\/speranza_disfunzioni_neurosviluppo-scaled.jpg","articleSection":["Scientific journals"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/","url":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/","name":"A hope for neurodevelopmental dysfunctions - Unione Italiana Nexmif","isPartOf":{"@id":"https:\/\/www.nexmif.it\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#primaryimage"},"image":{"@id":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#primaryimage"},"thumbnailUrl":"https:\/\/www.nexmif.it\/wp-content\/uploads\/2022\/05\/speranza_disfunzioni_neurosviluppo-scaled.jpg","datePublished":"2022-05-20T14:30:00+00:00","dateModified":"2022-05-30T07:54:25+00:00","breadcrumb":{"@id":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#primaryimage","url":"https:\/\/www.nexmif.it\/wp-content\/uploads\/2022\/05\/speranza_disfunzioni_neurosviluppo-scaled.jpg","contentUrl":"https:\/\/www.nexmif.it\/wp-content\/uploads\/2022\/05\/speranza_disfunzioni_neurosviluppo-scaled.jpg","width":2560,"height":1440,"caption":"Multi ethnic group of scientists working in laboratory interior"},{"@type":"BreadcrumbList","@id":"https:\/\/www.nexmif.it\/en\/scientific-journals\/hope-for-neurodevelopmental-dysfunctions\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.nexmif.it\/en\/"},{"@type":"ListItem","position":2,"name":"A hope for neurodevelopmental dysfunctions"}]},{"@type":"WebSite","@id":"https:\/\/www.nexmif.it\/en\/#website","url":"https:\/\/www.nexmif.it\/en\/","name":"Unione Italiana Nexmif","description":"","publisher":{"@id":"https:\/\/www.nexmif.it\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.nexmif.it\/en\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.nexmif.it\/en\/#organization","name":"Unione Italiana Nexmif","url":"https:\/\/www.nexmif.it\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.nexmif.it\/en\/#\/schema\/logo\/image\/","url":"https:\/\/www.nexmif.it\/wp-content\/uploads\/2015\/12\/logo-big_w.png","contentUrl":"https:\/\/www.nexmif.it\/wp-content\/uploads\/2015\/12\/logo-big_w.png","width":489,"height":202,"caption":"Unione Italiana Nexmif"},"image":{"@id":"https:\/\/www.nexmif.it\/en\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.nexmif.it\/en\/#\/schema\/person\/d7d9d7ada6f302c812dbc5408405c955","name":"tecnico","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.nexmif.it\/en\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/639d331f41d0f8de0b5c45c1b2f1d260?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/639d331f41d0f8de0b5c45c1b2f1d260?s=96&d=mm&r=g","caption":"tecnico"}}]}},"_links":{"self":[{"href":"https:\/\/www.nexmif.it\/en\/wp-json\/wp\/v2\/posts\/7354","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nexmif.it\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nexmif.it\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nexmif.it\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nexmif.it\/en\/wp-json\/wp\/v2\/comments?post=7354"}],"version-history":[{"count":0,"href":"https:\/\/www.nexmif.it\/en\/wp-json\/wp\/v2\/posts\/7354\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.nexmif.it\/en\/wp-json\/wp\/v2\/media\/8114"}],"wp:attachment":[{"href":"https:\/\/www.nexmif.it\/en\/wp-json\/wp\/v2\/media?parent=7354"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nexmif.it\/en\/wp-json\/wp\/v2\/categories?post=7354"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nexmif.it\/en\/wp-json\/wp\/v2\/tags?post=7354"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}